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Software tools from DMAS/LCIMB for the biophysical analysis of macromolecular assembly.

 Computer Requirements

DISCLAIMER

THIS SOFTWARE IS PROVIDED AS IS, AND WITH ALL FAULTS. THERE ARE NO WARRANTIES OF ANY KIND, EXPRESS, IMPLIED OR STATUTORY (INCLUDING, WITHOUT LIMITATION, TIMELINESS, TRUTHFULNESS, SEQUENCE, COMPLETENESS, ACCURACY, FREEDOM FROM INTERRUPTION). THERE ARE NO IMPLIED WARRANTIES ARISING FROM TRADE USAGE, COURSE OF DEALING, OR COURSE OF PERFORMANCE, OR THE IMPLIED WARRANTIES OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE. THERE IS NO WARRANTY THAT ANY SOFTWARE, INFORMATION, OR OUR EFFORTS WILL FULFILL ANY OF THE USERS PARTICULAR NEEDS OR PURPOSES

By downloading and using the software, you agree to cite the use of the software in publications (including the name and source), and to reference the original publication describing the method.

SEDFIT and SEDPHAT   

* Windows PC with at least 500 MHz, 256 MB RAM, Pentium or Xeon processor (Cyrix 3 processors may not work). Multi-core processors are supported and can significantly speed up many computations.  Best performance is obtained with high processor speed, large RAM, fast hard drive access is recommended, as well as a generous amount of graphics card memory.

* ~10 MB of disk space

* internet connection for accessing on-line help

Please sign up for the SEDFIT Users Group to post questions reaching ~ 250 other users, read exchanges of experience and tips for the SEDFIT software and AUC in general.  If you are using SEDPHAT, Please sign up to the SEDPHAT-L listserv for discussion of applications of SEDPHAT and questions of global analysis of ITC, AUC, and other biophysical techniques.  For both SEDFIT and SEDPHAT, you can sign up for update information at SEDFIT-UPDATE and SEDPHAT-UPDATE, respectively.

EVILFIT

Evilfit requires installat​ion of 32-bit Matlab Compiler Runtime library from Mathworks (MRC v 7.17, Release R2012a)​.  Note: the MRC will conflict with previous installations of MATLAB.

SEDFIT version 16.1c 
by schuckp@mail.nih.gov
 1/24/2024 1:45 PM
Major extension to nonideal sedimentation coefficient distribution​
 
SEDPHAT v. 14.0 
by schuckp@mail.nih.gov
 2/10/2017 9:55 AM

contains a new pipetting calculator to help in experimental design, and has improved performance with high-affinity systems (lower Kd-limits)​

 
ITCsy version 1a 
by schuckp@mail.nih.gov
 5/22/2015 9:44 AM

​This is a first version of a new sister-program to SEDPHAT specialized in the analysis of ITC data. 

It has advanced tools for global modeling and experimental design.

 
SEDFIT version 14.7g 
by schuckp@mail.nih.gov
 5/22/2015 8:44 AM

​This version has the new residuals histogram function and a few squashed bugs.

 
SEDPHAT v 12.1b 
by schuckp@mail.nih.gov
 1/9/2015 8:45 AM

​* new data generation tools for experimental planning

* visualization of data of heterogeneous interactions in the concentration plane

* sH/sD plot tool

 
(More Announcements...)
  
  
  
mlSEDFIT2.zip
  
5/23/2023 2:09 PM
mlSEDFIT.zip
  
5/14/2023 10:14 AM
sedfit16p50.zip
  
5/10/2023 2:16 PM
sedfit16p36.zip
  
2/18/2020 9:37 AM
sedfit16p35.zip
  
1/13/2020 9:50 AM
sedfit16-1c.zip
  
2/6/2019 2:19 PM
sedphat15-2b.zip
  
12/4/2018 11:35 AM
sedfit16-1.zip
  
9/18/2018 3:06 PM
sedphat15-2.zip
  
9/18/2018 2:32 PM
TOSE2p2.exe
  
2/23/2018 3:01 PM
sedfit154beta.zip
  
1/12/2018 12:15 PM
sedfit153.zip
  
11/7/2017 5:24 PM
sedphat14p0.zip
  
2/10/2017 9:54 AM
sedphat30b.zip
  
8/22/2016 3:46 PM
sedfit1501b.zip
  
1/29/2016 5:03 PM
sedfit1501.zip
  
12/11/2015 10:51 AM
sedfit14p81.zip
  
7/30/2015 12:52 PM
tose2.zip
  
7/30/2015 12:52 PM
ITCsy1a.zip
  
5/22/2015 9:44 AM
sedfit14-7g.zip
  
5/18/2015 9:35 AM
sedphat12p1c.zip
  
1/16/2015 2:07 PM
sedphat12p1b.zip
  
1/9/2015 8:43 AM
sedfit14p6e.zip
  
1/9/2015 8:42 AM
sedfit14p4fb.zip
  
8/30/2014 8:00 AM
SEDFIT-MSTAR.zip
  
2/11/2014 2:49 PM
sedfit144d.zip
  
10/29/2013 11:28 AM
sedphat10p58f.zip
  
5/24/2013 11:06 AM
sedfit14p3e.zip
  
5/22/2013 11:43 AM
sedfit143.zip
  
5/1/2013 12:35 PM
sedphat1058d.zip
  
4/16/2013 12:36 PM
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